Investigative Medicine Department - Welcome
Department of Investigative Medicine, Imperial College, London

Department of Metabolic Medicine Publications - 1975 - 1980

Barnes AJ, Bloom A, Crowley MF, Tuttlebee JW, Bloom SR and Turnell D. Is glucagon important in stable insulin-dependent diabetics? Lancet 2: 734-737, 1975.

Barros DAAJ, Bloom SR and Baron JH. Lancet 1: 886-887, 1975.

Bloom SR. Problems and perspectives of radioimmunoassay of gastrointestinal hormones. In: Proceedings 5th Int Symp on Gastrointestinal Motility, Leuven, Belgium, Typoff Press, Herentals, Belgium, 3-6 September, 1975.

Bloom, S. R. Gastrointestinal hormones. Proc R Soc Med 68, 710-711. 1975.

Bloom SR, Edwards AV, Hardy RN, Malinowska K and Silver M. J Physiol Lond 253: 135-155, 1975.

Bloom SR and Edwards AV. The release of pancreatic glucagon and inhibition of insulin in response to stimulation of the sympathetic innervation. J Physiol Lond 253: 157-173, 1975.

Bloom, S. R. Glucagon. Br J Hosp Med 13, 150-158. 1975.

Bloom SR and Polak JM. The role of VIP in pancreatic cholera. In: Gastrointestinal Hormones, Thompson J C (ed), Austin, University of Texas Press, 1975, p. 635-642.

Bloom SR and Ward AS. Failure of secretin release in patients with duodenal ulcer. BMJ 1: 126-127, 1975.

Bloom SR, Edwards AV, Hardy RN, Malinowska KW and Silver M. J Physiol Lond 244: 783-804, 1975.

Bloom SR. The development of a radioimmunoassay for secretin. In: Gastrointestinal Hormones, Thompson J C (ed), Austin, University of Texas Press, 1975, p. 257-268.

Hellemans J, Vantrappen G and Bloom SR. The hormonal control of lower oesophageal sphincter pressure. In: Proceedings 5th Int Symp on Gastrointestinal Motility, Leuven, Belgium, Typoff Press, Herentals, Belgium, 3-6 September, 1975.

Orton CI, Segal AW, Bloom SR and Clarke J. Hypersecretion of glucagon and gastrin in severely burnt patients. BMJ 2: 170-172, 1975.

Pallone F, Polak JM, Bloom SR, Joffe SN and Baron JH. Rendic Gastroenterol 7: 60-64, 1975.

Polak JM, Pearse AGE, Bloom SR, Buchan AMJ, Rayford PL and Thompson JC. Identification of cholecystokinin-secreting cells. Lancet 2: 1016-1018, 1975.

Polak JM, Pearse AGE, Joffe S and Bloom SR. Quantification of secretin release by acid, using immunocytochemistry and radioimmunoassay. Experientia 31: 462-464, 1975.

Polak JM, Pearse AGE, Grimelius L, Bloom SR and Arimura A. Growth hormone release-inhibiting hormone in gastrointestinal and pancreatic D cells. Lancet 1: 1220-1225, 1975.

Polak JM, Pearse AGE, Bloom SR and Joffe SN. Quantification of physiological changes in gut endocrine cells: immunocytochemical and radioimmunoassays of secretin cell function. Acta Hepato-Gastroenterol 1975.

Rambaud J, Modigliani R, Matuchansky C, Bloom SR, Said S, Pessayre D and Bernier J. Pancreatic cholera studies on tumoral secretions and pathophysiology of diarrhoea. Gastroenterology 69: 110-122, 1975.

Russell RCG, Bloom SR, Davies WA, Polak JM and Read PI. Hypergastrinaemia in a peptic ulcer patient with antral gastrin cell hyperplasia. BMJ 4: 441, 1975.

Russell RCG, Walker CJ and Bloom SR. Hyperglucagonaemia in the surgical patient. BMJ 1: 10-12, 1975.

Seif, F. J., Sadowski, P., Heni, F., Fischer, R., Bloom, S. R., and Polak, J. M. Das vasoaktive intestinale polypeptid beim Verner-Morrison syndrome. Dtsch Med Wschr 100, 399-405. 1975.

Swift PGF, Bloom SR and Harris F. Watery diarrhoea and ganglioneuroma with secretion of vasoactive intestinal peptide. Arch Dis Child 50: 896-899, 1975.

Thorner MO, Chait A, Aitken M, Benker, Mortimer CH, Sanders P, Bloom SR and Besser GM. Bromocriptine treatment of acromegaly. BMJ 1: 299-303, 1975.

Ward AS and Bloom SR. Effect of vagotomy on secretin release in man. Gut 1975.

Adrian TE, Bloom SR, Besterman HS, Barnes AJ, Cooke TJC, Russell RCG and Faber RG. Mechanism of pancreatic polypeptide release in man. Lancet 1: 161-163, 1976.

Adrian TE, Bloom SR, Bryant MG, Polak JM, Heitz P and Barnes AJ. Distribution and release of human pancreatic polypeptide. Gut 17: 940-944, 1976.

Alford FP, Bloom SR and Nabarro JDN. Glucagon metabolism in man, studies on the metabolic clearance rate and the plasma acute disappearance time of glucagon in normal anddiabetic subjects. J Clin Endocrinol Metab 42: 830-838, 1976.

Barnes AJ and Bloom SR. Pancreatectomised man: a model for diabetes without glucagon. Lancet 1976.

Batstone GF, Alberti KGMM, Hinks L, Smythe P, Laing JE, Ward CM, Ely DW and Bloom SR. Metabolic studies in subjects following thermal injury, intermediary metabolites, hormones and tissue oxygenation. Burns 2: 207-225, 1976.

Bloom SR, Edwards AV, Hardy RN and Silver M. J Physiol Lond 261: 271-283, 1976.

Bloom SR and Iversen J. Gut hormones and the alpha cell. Metabolism 25: 1457-1458, 1976.

Bloom SR, Barnes AJ, Bryant MG and Alberti KGMM. Plasma glucagon in diabetes resulting from total pancreatectomy. Metabolism 25: 1481-1482, 1976.

Bloom SR, Mitznegg P and Bryant MG. Measurement of human plasma motilin. Scand J Gastroenterol 11: 47-52, 1976.

Bloom SR, Johnson RH, Park DM, Rennie MJ and Sulaiman WR. Differences in the metabolic and hormonal response to exercise between racing cyclists and untrained individuals. J Physiol Lond 258: 1-18, 1976.

Bloom SR. Gastrointestinal effects of somatostatin. In: Polypeptide Hormones: molecular and cellular aspects, CIBA Foundation Symposium (new series) Ebevier/Excerpta Medica/North Holland, Amsterdam, 1976, p. 323-332.

Bloom SR and Polak JM. VIP measurement in distinguishing Verner-Morrison syndrome and pseudo Verner-Morrison syndrome. Clin Endocrinol 5: 223-228, 1976.

Bloom, S.R. Hormones of the gut. Medicine, 818-820. 1976.

Bloom SR. Blood glucose control by direct islet innervation. Horm Metab Res S 6: 85-90, 1976.

Bryant MG, Bloom SR, Polak JM, Albuquerque RH, Modlin I and Pearse AGE. Possible dual role for vasoactive intestinal peptide as gastrointestinal hormone and neurotransmitter substance. Lancet 1: 991-993, 1976.

Buchanan N, Moodley G, Eyberg C, Bloom SR and Hansen JDL. Hypoglycaemia associated with severe kwashiokor. S Afr Med J 50: 1442-1446, 1976.

Domschke W, Lux G, Mitznegg P, Rosch W, Domschke S, Bloom SR, W E and Demling L. Endogenous motilin and lower oesophageal sphincter pressure in man: clue to an association. Acta Hepato-Gastroenterol 23: 273-275, 1976.

Domschke W, Lux G, Mitznegg P, Rosch W, Domschke S, Bloom SR, W E and Demling L. Relationship of plasma motilin response to lower oesophageal sphincter pressure in man. Scand J Gastroenterol 11: 81-84, 1976.

Gagel RF, Costanza ME, Delellis RA, Norton RA, Bloom SR, Miller HH, Ucci A and Nathanson L. Streptozotocin-treated Verner-Morrison syndrome plasma vasoactive intestinal peptide and tumour responses. Arch Intern Med 136: 1429-1435, 1976.

Heitz P, Polak JM, Bloom SR and Pearse AGE. Identification of the D -cell as the source of human pancreatic polypepide (HPP). Gut 17: 755-758, 1976.

Heitz P, Polak JM, Bloom SR, Adrian TE and Pearse AGE. Cellular origin of human pancreatic polypeptide (HPP) in endocrine tumours of the pancreas. Virchows Arch [Cell Pathol] 21: 259-265, 1976.

Hellemans J, Vantrappen G and Bloom SR. Endogenous motilin and the LES pressure. Scand J Gastroenterol 11: 67-73, 1976.

Mitznegg P, Bloom SR, Christofides N, Besterman H, Domschke W, Domschke S, W E and Demling L. Release of motilin in man. Scand J Gastroenterol 11: 53-56, 1976.

Mitznegg P, Bloom SR, Domschke W, Domschke S and W E. Release of motilin after duodenal acidification. Lancet 1: 888-889, 1976.

Polak JM, Bloom SR, Adrian TE, Heights P, Bryant MB and Pearse AGE. Pancreatic polypeptide in insulinomas, gastrinomas, VIPomas and glucagonomas. Lancet 1: 328-330, 1976.

Polak, J. M., Bloom, S. R., and Pearse, A.G.E. Gut endocrinology: correlation of physiology and morphology. Clinical Endocrinology 5, 205-216. 1976.

Polak JM, Hobbs S, Bloom SR, Solcia E and Pearse AGE. Distribution of a bombesin-like peptide in human gastrointestinal tract. Lancet 1976.

Russell, R. C. G., Bloom, S. R., Fielding, L. P., and Bryant, M. G. Current problems in the measurement of gastrin release. A reproducible measure of physiological gastrin release. Postgraduate Medical Journal 52, 645-650. 1976.

Soler, N. G., Oates, G. D., Malins, J. M., Cassar, J., and Bloom, S. R. Glucagonoma syndrome in a young man. Proc R Soc Med 69, 429-431. 1976.

Thomson JPS and Bloom SR. Plasma enteroglucagon and plasma volume change after gastric surgery. Clin Sci 51: 177-183, 1976.

Villar HV, Fender HR, Rayford PL, Bloom SR, Ramus NI and Thompson JC. Suppression of gastrin release and gastric secretion by gastric inhibitory polypeptide (GIP) and vasoactive intestinal polypeptide (VIP). Ann Surg 184: 97-102, 1976.

Alberti KGMM, Barnes AJ, Bloom SR, Holloway PAH, Johnson DG and Orskov H. The role of hormones in the pathogenesis of severe diabetic ketoacidosis - implications for treatment. In: Diabetes, Bajaj J S (ed) Excerpta Medica, Amsterdam, 1977, p. 367-373.

Alford FP, Bloom SR and Nabarro JDN. Glucagon levels in normal and diabetic subjects: Use of a specific immuno-absorbant for glucagon radioimmunoassay. Diabetologia 13: 1-6, 1977.

Aynsley-Green A, Bloom SR, Williamson DH and Turner RC. Endocrine and metabolic response in the human newborn to first feed of breast milk. Arch Dis Child 52: 291-295, 1977.

Aynsley-Green A, Bloom SR, Williamson DH and Turner RC. Metabolic and endocrine responses to feeding in the human newborn. In: Recent Progress in Paediatric Endocrinology, Chiumello G & Laron Z (eds), Academic Press, London, 1977.

Barnes AJ, Bloom SR, Alberti KGMM, Smythe P, Alford FP and Chisholm DJ. Ketoacidosis in pancreatectomized man. N Engl J Med 296: 1250-1253, 1977.

Barnes AJ, Bloom SR, Mashiter K, Alberti KGMM, Smythe P and Turnell D. Persistent metabolic abnormalities in diabetes in the absence of glucagon. Diabetologia 13: 71-75, 1977.

Blauth CIA, Sonksen PH, Tompkins CV and Bloom SR. Clin Endocrinol 6: 17-25, 1977.

Bloom SR. Gastrointestinal hormones. In: Gastrointestinal Physiology II, Crane R K (ed), University Park Press, Baltimore, 1977, p. 72-103.

Bloom SR. Gut hormones and disease. In: Advanced Medicine, Besser M (ed), Pitman Medical Publishing Co Ltd, Tunbridge Wells, Kent, 1977, p. 348-358.

Bloom SR, Edwards AV and Hardy RN. J Physiol Lond 269: 131-154, 1977.

Bloom SR, Edwards AV, Hardy RN and Malinowska KW. Experientia 33: 362-363, 1977.

Bloom SR and Polak JM. The new peptide hormones of the gut. In: Progress in Gastroenterology, Jerzy Glass G B (ed), Grune & Stratton, New York, 1977, p. 109-152.

Bloom SR. Glucagonomas and skin disease. In: Glucagon: its role in physiology and clinical medicine, Foa P P, Bajaj J S & Foa N L (eds), Springer Verlag, New York, 1977, p. 759-764.

Bloom SR. Hormones of the gastrointestinal tract. In: Recent Advances in Medicine, Baron D N, Compston N & Dawson A M (eds) Churchill Livingstone, Edinburgh, 1977, p. 357-386.

Domschke W, Greenberg GR, Domschke S, Bloom SR, Mitznegg P, Spr W and Demling L. Endogenous acid releases secretin in man. Acta Hepato-Gastroenterol 24: 362-363, 1977.

Greenberg GR, Mitznegg P and Bloom SR. Effect of pancreatic polypeptide on DNA-synthesis in the pancreas. Experientia 33: 1332-1333, 1977.

H WH, Bloom SR, Mitznegg P, Domschke W, Domschke S, Belohlavek D, Demling L and W E. Plasma secretin and pancreatic bicarbonate response to exogenous secretin in man. Gut 18: 191-195, 1977.

Isenberg JI, Cano R and Bloom SR. Effect of graded amounts of acid instilled into the duodenum on pancreatic bicarbonate secretion and plasma secretin in duodenal ulcerpatients and normal subjects. Gastroenterology 72: 6-8, 1977.

Joffe SN, Polak JM, Pallone F, Bloom SR, Gasking RJ and Barros DAAJBJH. Gastrin, antral G cells and gastric acid in secretagogue-induced and anti-histamine-inhibited duodenal ulcers. Scand J Gastroenterol 12: 27-32, 1977.

Mitznegg P, Bloom SR, Domschke W, Domschke S, W E and Demling L. Pharmacokinetics of motilin in man. Gastroenterology 72: 413-416, 1977.

Mitznegg P, Bloom SR, Domschke W, H WH, Domschke S, Belohlavek D, W E and Demling L. Effect of secretin on plasma motilin in man. Gut 18: 468-471, 1977.

Pearse, A. G. E., Polak, J. M., and Bloom, S.R. The newer gut hormones. Cellular sources, physiology, pathology and clinical aspects. Gastroenterology 72, 746-761. 1977.

Polak JM, Sullivan SN, Bloom SR, Facer P and Pearse AGE. Enkephalin-like immunoreactivity in the human gastrointestinal tract. Lancet 1: 972-997, 1977.

Polak JM, Sullivan SN, Bloom SR, Buchan AMJ, Facer P, Brown MR and Pearse AGE. Neurotensin in human intestine: radaioimmunoassay and specific localisation to the N cell. Nature 270: 183-185, 1977.

Polak JM, Pearse AGE, Szelke M, Bloom SR, Hudson D, Facer P, Buchan AMJ, Bryant MG, Christofides N and MacIntyre I. Specific immunostaining of CCK cells by use of synthetic fragment antisera. Experientia 33: 762-763, 1977.

Russell CGR, Pardy BJ, Carruthers ME and Bloom SR. Plasma glucagon levels in haemorrhagic shock. Br J Surg 64: 285-289, 1977.

Soerjodibroto WS, Heard CRC, James WPT, Few JD and Bloom SR. Metabolic and hormonal changes after surgery: hyperinsulinaemia during glucose infusion. Eur J Clin Invest 7: 579-586, 1977.

Strunz UT, Walsh JH, Bloom SR, Thompson MR and Grossman MI. Gastroenterology 73: 768-771, 1977.

Turner C, Harris E, Bloom SR and Uren C. Relation of fasting plasma glucose concentration to plasma insulin and glucagon concentrations. Diabetes 26: 166-171, 1977.

Adrian TE, Greenberg RG, Besterman HS and Bloom SR. Pharmacokinetics of pancreatic polypeptide in man. Gut 19: 907-909, 1978.

Adrian TE, Greenberg RG, Besterman HS, McCloy RF, Chadwick VS, Barnes AJ, Mallinson CN, Baron JH, Alberti KGGM and Bloom SR. PP infusion in man - summary of initial investigations. In: Gut Hormones, Bloom S R (ed) Churchill Livingstone, Edinburgh, 1978, p. 265-267.

Adrian TE, Bloom SR, Besterman HS and Bryant MG. PP - physiology and pathology. In: Gut Hormones, Bloom S R (ed) Churchill Livingstone, Edinburgh, 1978, p. 254-260.

Adrian TE, Bloom SR, Hermansen K and Iversen J. Diabetologia 14: 413-471, 1978.

Barnes AJ, Kohner EM, Bloom SR, Johnston DG, Alberti KGMM and Smythe P. Importance of pituitary hormones in aetiology of diabetic ketoacidosis. Lancet 1: 1171-1174, 1978.

Barros DAA, Bloom SR and Baron JH. Inhibition by somatostatin (growth-hormone release-inhibiting hormone, GH-RIH) of gastric acid and pepsin and G-cell release of gastrin. Gut 19: 315-320, 1978.

Besterman HS, Bloom SR, Sarson DL, Blackburn AM, Johnston DI, Patel HR, Stewart SW, Modigliani R, Guerin S and Mallinson CN. Gut-hormone profile in coeliac disease. Lancet 1: 785-788, 1978.

Bloom SR and Edwards AV. Certain pharmacological characteristics of the release of pancreatic glucagon in response to stimulation of the splanchnic nerves. J Physiol Lond 280: 25-35, 1978.

Bloom SR, Edwards AV and Hardy RN. J Physiol Lond 280: 37-53, 1978.

Bloom SR, Polak JM and Besterman HS. Gut hormone profile in coeliac disease: a characteristic pattern of pathology. In: Perspectives in coeliac disease< mcNicholl B, McCarthy C F & Fotytell P F (eds), MTP Press Ltd, Lancaster, England 1978: 399- 348, 1978, p. 924-947.

Bloom SR. Physiology of the neuroendocrine system. In: Surgical Endocrinology: Clinical Syndromes, Friesen S R (ed) J B Lipincott Company, Philadelphia, Toronto, 1978, p. 35-42.

Bloom SR, Edwards AV and Hardy RN. The role of the autonomic nervous system in the control of glucagon, insulin and pancreatic polypeptide release from the pancreas. J Physiol Lond 280: 9-23, 1978.

Bloom, S.R. Somatostatin and the gut. Gastroenterology 75, 145-147. 1978.

Bloom SR, Polak JM and West AM. Somatostatin content of pancreatic endocrine tumors. Metabolism 27: 1235-1238, 1978.

Bloom SR and Polak JM. The new peptide hormones of the gut and their clinical significance. In: Verlag Gerhard Witzstrock Baden-Baden, Bartelheimer H, Classen M & Ossenberg F-W (eds), 1978.

Bloom SR. Vasoactive Intestinal Peptide. In: Methods of Hormone Radioimmunoassay, Jaffe B M & Behrman H R (eds), Academic Press, New York, 1978, p. 553-565.

Bloom, S. R. and Polak, J. M. The new peptide hormones of the gut and their clinical significance. Acta Gastroenterologica Belgica 41, 371-393. 1978.

Bloom SR and Polak JM. Enteropancreatic axis. In: Advances in Exp Med Biol, Grossman M, Speranza V, Basso N & Lezoche E (eds), Plenum Press, New York, 1978, p. 151-163.

Bloom, S. R. and Polak, J. M. Hormones and food utilization. Proc Nutr Soc 37, 259-271. 1978.

Bloom SR, Mitchell SJ, Greenberg GR, Christofides N, Domschke W, Domschke S, Mitznegg P and Demling L. Release of VIP, secretin and motilin after duodenal acidification in man. Acta Hepato-Gastroenterol 25: 365-368, 1978.

Bloom SR and Polak JM. The glucagonoma syndrome. In: Advances in Exp Med & Biol, Grossman M, Speranza V, Basso N & Lezoche E (eds), Plenum Press, New York, 1978, p. 183-194.

Bloom, S.R. Gut and brain - endocrine connections. The Goulstonian Lecture 1979. J R Coll Surg Lond 14, 51-57. 1978.

Bloom SR. Signals for glucagon secretion. In: Hepatotrophic Factors, Porter R & Whelan J (eds), Elsevier, Excerpta Medica, North-Holland, Amsterdam, 1978, p. 161-171.

Bloom SR, West AM, Polak JM, Barnes AJ and Adrian TE. Hormonal contaminants of insulin. In: Gut Hormones, Bloom S R (ed) Churchill Livingstone, Edinburgh, 1978, p. 318-322.

Bloom SR and Polak JM. Gut hormone overview. In: Gut Hormones, S R Bloom (ed), Churchill Livingstone, Edinburgh, 1978.

Bloom SR. Vasoactive intestinal peptide, the major mediator of the WDHA (pancreatic cholera) syndrome: value of measurement in diagnosis and treatment. Am J Dig Dis 23: 373-376, 1978.

Bloom SR. VIP and watery diarrhoea. In: Gut Hormones, Bloom S R (ed) Churchill Livingstone, Edinburgh, 1978, p. 538-588.

Bretholz A, Levesque D, Voirol M, Tiscornia OM, Bloom SR and Sarles H. Digestion 17: 437-440, 1978.

Buchan AMJ, Polak JM, Sullivan NS, Bloom SR, Brown M and Pearse AGE. Neurotensin in the gut. In: Gut Hormones, Bloom S R (ed) Churchill Livingstone, Edinburgh, 1978, p. 544-549.

Christofides ND and Bloom SR. Plasma motilin levels in duodenal ulcer and effect of a truncal vagotomy and hypoglycaemia. Experientia 34: 809-810, 1978.

Christofides ND, Bloom SR and Besterman HS. Physiology of motilin. In: Gut Hormones, Bloom S R (ed) Churchill Livingstone, Edinburgh, 1978, p. 343-350.

Domschke S, Domschke W, Bloom SR, Mitznegg P, Mitchell S, Lux G, Strunz U and Demling L. Pharmacokinetics and pharmacodynamics of VIP in man. In: Gut Hormones, Bloom S R (ed) Churchill Livingstone, Edinburgh, 1978, p. 475-478.

Domschke S, Domschke W, Bloom SR, Mitznegg P, Mitchell SJ, Lux G and Strunz U. Vasoactive intestinal peptide in man: pharmacokinetics, metabolic and circulatory effects. Gut 19: 1049-1053, 1978.

Domschke W, Lux G, Domschke S, Strunz U, Bloom SR and Wunsch E. Effects of vasoactive intestinal peptide on resting and pentagastrin-stimulated lower esophageal sphincter pressure. Gastroenterology 75: 9-12, 1978.

Edwards AV and Bloom SR. Nervous control of pancreatic hormones. In: Gut Hormones, S R Bloom (ed) Churchill Livingstone, Edinburgh, 1978, p. 394-405.

Edwards AV, Bircham PMM, Mitchell SJ and Bloom SR. Experientia 34: 1186-1187, 1978.

Greenberg GR and Bloom SR. Role of secretin in man. In: Gut Hormones, S R Bloom (ed) Churchill Livingstone, Edinburgh, 1978, p. 182-192.

Greenberg RG, McCloy RF, Adrian TE, Baron JH and Bloom SR. Effect of bovine pancreatic polypeptide on gastric acid and pepsin output in man. Acta Hepato-Gastroenterol 25: 384-387, 1978.

Greenberg RG, McCloy RF, Adrian TE, Chadwick VS, Baron JH and Bloom SR. Inhibition of pancreas and gall bladder by pancreatic polypeptide. Lancet 2: 1280-1282, 1978.

Joffe SN, Elias E, Rehfeld JF, Polak JM, Bloom SR and Welbourn RB. Clinically silent gross hypergastrinaemia from a multiple hormone-secreting pancreatic apudoma. Br J Surg 65: 277-280, 1978.

Kingham JGC, Dick R, Bloom SR and Frankel RJ. VIPoma: localisation by percutaneous transhepatic portal venous sampling. BMJ 2: 1682-1683, 1978.

Lennon, J., Bloom, S. R., and Sircus, W. Studies on blood levels of vasoactive inhibitory peptide (VIP) and pancreatic polypeptide (PP) and their relation to clinical behaviour ina case of Verner-Morrison syndrome. Ital J Gastroenterol 10, 104-106. 1978.

Lucas A, Bloom SR and Aynsley-Green A. Metabolic and endocrine events at the time of the first feed of human milk in preterm and term infants. Arch Dis Child 53: 731-736, 1978.

Mallinson CN and Bloom SR. The hyperglycemic, cutaneous syndrome: pancreatic glucagonoma. In: Surgical Endocrinology: Clinical Syndromes, Friesen S R (ed) J B Lippincott Company, Philadelphia, Toronto, 1978, p. 171-202.

McDonald TJ, Nilsson G, Vagne M, Ghatei M, Bloom SR and Mutt V. Gut 19: 767-774, 1978.

Mitchell SJ and Bloom SR. Measurement of fasting and postprandial plasma VIP in man. Gut 19: 1043-1048, 1978.

Mitznegg P, Domschke W, Bloom SR, Schubert E, Domschke S, Strunz U, K R, W E and Demling L. Physiology of motilin 1. In: Gut Hormones, Bloom S R (ed) Churchill Livingstone, Edinburgh, 1978, p. 339-342.

Modlin IM, Bloom SR and Mitchell SJ. Experimental evidence for vasoactive intestinal peptide as the cause of the watery diarrhoea syndrome. Gastroenterology 75: 1051-1054, 1978.

Modlin IM, Mitchell SJ and Bloom SR. The systemic release and pharmacokinetics of VIP. In: Gut Hormones, Bloom S R (ed) Churchill Livingstone, Edinburgh, 1978, p. 470-474.

Modlin, I. M. and Bloom, S. R. VIPomas and the watery diarrhoea syndrome. S Afr Med J 54, 53-56. 1978.

Modlin IM, Mitznegg P and Bloom SR. Gut 19: 399-402, 1978.

Modlin IM, Bloom SR and Mitchell SJ. Plasma vasoactive intestinal polypeptide (VIP) levels and intestinal ischaemia. Experientia 34: 535-536, 1978.

Modlin IM, Bloom SR, Barnes AJ and Welbourn RB. Cure of intractable watery diarrhoea by excision of a VIPoma. Br J Surg 65: 234-236, 1978.

Modlin IM, Bloom SR and Mitchell S. VIP: The cause of the watery diarrhoea syndrome. In: Advances in Exp Med & Biol, Grossman M, Speranza V, Basso N & Lezoche E (eds), Plenum Press, New York, 1978, p. 195-201.

Polak JM and Bloom SR. Peptide hormones of the alimentary tract. In: Rev Esp Enf Ap Digest 6th Wrld Congress of Gastroenterology, Quariennal Reviews, 1978, p. 107-134.

Polak JM, Sullivan SN, Buchan AM, Bloom SR, Facer P, Hudson D and Pearse AGE. Endorphins. In: Gut Hormones, Bloom S R (ed) Churchill Livingstone, Edinburgh, 1978, p. 501-506.

Polak JM, Bishop AE and Bloom SR. Gastrointestinal hormones. In: Gastroenterologia, Koogan G (ed) Rio de Janeiro, 1978, p. 924-947.

Polak JM, Buchan AMJ, Czyowska W, Solcia E, Bloom SR and Pearse AGE. Bombesin in the gut. In: Gut Hormones, Bloom S R (ed) Churchill Livingstone, Edinburgh, 1978, p. 541-543.

Polak JM, Bloom SR, Bishop AE and McCrossan MV. D cell pathology in duodenal ulcers and achlorhydria. Metabolism 27: 1239-1242, 1978.

Polak JM and Bloom SR. Peptidergic innervation of the gastrointestinal tract. In: Advances in Exp Med Biol, Grossman M, Speranza V, Basso N & Lezoche E (eds), Plenum Press, New York, 1978, p. 27-49.

Polak, J. M. and Bloom, S.R. Peptidergic nerves of the gastrointestinal tract. Invest Cell Pathol 1, 301-326. 1978.

Quik M, Iversen LL and Bloom SR. Biochem Pharmacol 27: 2209-2212, 1978.

Royston CMS, Polak J, Bloom SR, Cooke WM, Russell CGR, Pearse AGE, Spencer J, Welbourn RB and Baron JH. G cell population of the gastric antrum, plasma gastrin and gastric acid secretion in patients with and without duodenal ulcer. Gut 19: 689-698, 1978.

Solcia E, Polak JM, Pearse AGE, Forssman WG, Larsson L-I, Sundler F, Lechago J, Grimelius L, Fujita T, Creutzfeldt W, Gepts W, Faulkmer S, Lefranc G, Heinz P, Hage EBAMJ, Bloom SR and Grossman MI. Classification of gastroenteropancreatic endocrine cells. In: Gut Hormones, Bloom S R (ed) Churchill Livingsyone, Edinburgh 1978, 1978, p. 40-48.

Vantrappen G, Janssens J, Hellemans J, Christofides N and Bloom SR. Studies on the interdigestive (migrating) motor complex in man. In: Proc VIth Inter Symp Gastrointestinal Motility, Duthie H (ed) MTP Press, Edinburgh, 1978.

Walsh CH, Malins JM and Bloom SR. Diabetes mellitus in idiopathic haemochromatosis. BMJ 2: 1267-1268, 1978.

Welbourn RB, Polak JM, Bloom SR, Pearse AGE and Galland RB. Apudomas of the pancreas. In: Gut Hormones, Bloom S R (ed) Churchill Livingstone, Edinburgh, 1978, p. 561-569.

Wharton J, Polak JM, Bloom SR, Ghatei MA, Solcia E, Brown MR and Pearse AGE. Bombesin-like immunoreactivity in the lung. Nature 273: 769-770, 1978.

Adrian TE, Besterman HS, Mallinson CN, Garalotis C and Bloom SR. Impaired pancreatic polypeptide release in chronic pancreatitis with steatorrhoea. Gut 20: 98-101, 1979.

Adrian TE, Besterman HS, Mallinson CN, Pera A, Redshaw MR, Wood TP and Bloom SR. Plasma trypsin in chronic pancreatitis and pancreatic adenocarcinoma. Clin Chim Acta 97: 205-212, 1979.

Adrian TE, Barnes AJ and Bloom SR. Hypotrypsinaemia in diabetes mellitus. Clin Chim Acta 97: 213-216, 1979.

Adrian TE, Besterman HS and Bloom SR. The importance of cholinergic tone in the release of pancreatic polypeptide by gut hormones in man. Life Sci 24: 1989-1994, 1979.

Adrian TE, Besterman HS, Mallinson CN, Greenberg GR and Bloom SR. Inhibition of secretin stimulated pancreatic secretion by pancreatic polypeptide. Gut 20: 37-40, 1979.

Albuquerque RH, Owens CWI and Bloom SR. Experientia 35: 1496-1497, 1979.

Aynsley-Green A, Lucas A and Bloom SR. The effect of feeds of different composition on enteroinsular hormone secretion in the first hours of life in human neonates. Acta Paediatr Scand 68: 265-270, 1979.

Barraclough MA and Bloom SR. VIPoma of the pancreas. Arch Int Med 139: 467-471, 1979.

Besterman HS, Cook GC, Sarson DL, Christofides ND, Bryant MG, Gregor M and Bloom SR. Gut hormones in tropical malabsorption. BMJ 1: 1252-1255, 1979.

Bj OG, Adrian TE, Dawson J, McCloy RF, Greenberg GR, Bloom SR and Chadwick VS. Effects of gastrointestinal hormones on fasting gall bladder storage patterns in man. Eur J Clin Invest 9: 293-300, 1979.

Blackburn AM and Bloom SR. A radioimmunoassay for neurotensin in human plasma. J Endocrinol 83: 175-181, 1979.

Bloom SR and Polak JM. Neuropeptides in the gut and other peripheral tissues. In: Brain Peptides: A New Endocrinology, Gotto A M Jr, Peck E J Jr & Boyd A E (eds) Biomedical Press, Elsevier/North-Holland, Amsterdam, 1979, p. 103-117.

Bloom, S. R. Alimentary hormones. Medicine 15, 733-736. 1979.

Bloom, S. R., Polak, J. M., and Welbourn, R. B. Pancreatic apudomas. Wld J Surg 3, 587-595. 1979.

Bloom SR, Adrian TE, Barnes AJ and Polak JM. Autoimmunity in diabetics induced by hormonal contaminants of insulin. Lancet 1: 14-17, 1979.

Bloom SR. Pathophysiology of duodenal ulcer disease. In: Gastrins and the Vagus, Rehfeld J F & AMdrup E (eds) Academic Press, London 1979: 173 -174, 1979, p. 173-174.

Bloom, S.R. Hormonal peptides of the gastrointestinal tract. Eur J Clin Invest 9, 111-113. 1979.

Bloom SR and Polak JM. Glucagonomas, VIPomas and PPomas. In: Gut Peptides, Miyoshi A (Ed), Kodansha Ltd, Tokyo and Elsevier North-Holland Biomedical Press, Amsterdam, 1979, p. 327-336.

Bloom SR and Polak JM. The effect of gastrointestinal disease on gut hormone release. In: Gut Peptides, Miyoshi A (Ed), Kodansha Ltd, Tokyo and Elsevier North-Holland Biomedical Press, Amsterdam, 1979, p. 356-366.

Bloom SR and Polak JM. The hormones of the gastrointestinal tract. In: Scientific Basis of Gastroenterology, Duthe H L & Wormsley K G (eds), Churchill Livingstone, Edinburgh, 1979, p. 71-111.

Bloom SR. Gastrointestinal hormones (1): pancreatic polypeptide, motilin, gastric inhibitory peptide, neurotensin, enteroglucagon and others. In: Hormones in Blood, Gray C H & James V H T (eds) 3rd edition, Academic Press, London, 1979, p. 321-356.

Bryant MG and Bloom SR. Gut 20: 653-659, 1979.

Chalmers RJ, Bloom SR, Duncan G, Johnson RH and Sulaiman WR. The effect of somatostatin on metabolic and hormonal changes during and after exercise. Clin Endocrinol 10: 451-458, 1979.

Christofides ND, Bloom SR, Besterman HS, Adrian TE and Ghatei MA. Release of motilin by oral and intravenous nutrients in man. Gut 20: 102-106, 1979.

Christofides ND, Modlin IM, Fitzpatrick ML and Bloom SR. Effect of motilin on the rate of gastric emptying and gut hormone release during breakfast. Gastroenterology 76: 903-907, 1979.

Christofides ND, Sarson DL, Albuquerque RH, Adrian TE, Ghatei MA, Modlin IM and Bloom SR. Release of gastrointestinal hormones following an oral water load. Experientia 35: 1521-1522, 1979.

Greenberg GR, Domschke S, Domschke W, R W and Bloom SR. Effect of low dose secretin and caerulein on pure pancreatic bicarbonate secretion and plasma secretin in man. Acta Hepato-Gastroenterol 26: 478-481, 1979.

Greenberg GR, McCloy RF, Chadwick VS, Adrian TE, Baron JH and Bloom SR. Dig Dis Sci 24: 11-14, 1979.

Jenkins DJA, Taylor RH, Nineham R, Goff DV, Bloom SR, Sarson D and Alberti KGMM. Combined use of guar and acarbose in reduction of postprandial glycaemia. Lancet 2: 924-927, 1979.

Long RG, Barnes AJ, Adrian TE, Mallinson CN, Brown MR, Vale W, Christofides ND and Bloom SR. Suppression of pancreatic endocrine tumour secretion by long- acting somatostatin analogue. Lancet 1979.

McDonald TJ, J H, Nilsson G, Vagne M, Ghatei M, Bloom SR and Mutt V. Biochem Biophys Res Commun 90: 227-223, 1979.

Meldrum BS, Horton RW, Bloom SR, Butler J and Keenan J. Epilepsia 20: 527-533, 1979.

Polak JM and Bloom SR. Motilin and neurotensin. In: Clinics in Endocrinology & Metabolism, Buchanan K D (ed) W B Saunders, London, 1979, p. 401-411.

Polak JM and Bloom SR. Las hormonas del tracto gastrointestinal. In: Adelantos En Gastroenterologia, Fernandez L B & De Paula A O F (eds) Potosi 42 15, Buenos Aires, Argentina, Chapter 3, 1979.

Polak JM and Bloom SR. The neuroendocrine design of the gut. J Clin Endocrinol Metab 8: 313-330, 1979.

Polak JM and Bloom SR. The neuropeptides and the antrum. In: Gastrins and the Vagus, Rehfeld J F & Amdrup E (eds), Academic Press, London, 1979, p. 15-30.

Polak, J. M. and Bloom, S.R. Neuropeptides of the gut: a newly discovered major control system. Wld J Surg 3, 393-406. 1979.

Polak, J. M. and Bloom, S.R. The diffuse neuroendocrine system. Journal of Histochemistry and Cytochemistry 27, 398-400. 1979.

Polak JM and Bloom SR. Distribution of neuropeptides and their influence on disease. In: Gut Peptides, Miyoshi A (Ed), Kodansha Ltd, Tokyo and Elsevier North-Holland Biomedical Press, Amsterdam, 1979, p. 258-267.

Timson CM, Polak JM, Wharton J, Ghatei MA, Bloom SR, Usellini L, Capella C, Solcia E, Brown MR and Pearse AGE. Histochemistry 61: 213-221, 1979.

Van NS, Polak JM, Bloom SR and Bryant MG. Vasoactive intestinal polypeptide in the pituitary pars nervosa. Neuropathol Appl Neurobiol 5: 149-153, 1979.

Vantrappen G, Janssens J, Peeters TL, Bloom SR, Christofides ND and Hellemans J. Motilin and the interdigestive migrating motor complex in man. Dig Dis Sci 24: 497-500, 1979.

Wharton J, Polak JM, Bloom SR, Will JA, Brown MR and Pearse AGE. Invest Cell Pathol 2: 3-10, 1979.

Wharton J, Polak JM, Bryant MG, Van NS, Bloom SR and Pearse AGE. Vasoactive intestinal polypeptide (VIP)-like immunoreactivity in salivary glands. Life Sci 25: 273-280, 1979.

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