Abbott CR, Rossi M, Kim MS, AlAhmed SH, Taylor GM, Ghatei MA, Smith DM and Bloom SR. Investigation of the melanocyte stimulating hormones on food intake - Lack of evidence to support a role for the melanocortin-3-receptor. Brain Res 869: 203-210, 2000.

Bailey CJ, Bates SH, Turner SL, Rossi M, Morgan I and Bloom SR. Pharm Pharmacol Commun 6: 35-39, 2000.

Brynes AE, Edwards CM, Jadhav A, Ghatei MA, Bloom SR and Frost GS. Diet-induced change in fatty acid composition of plasma triacylglycerols is not associated with change in glucagon-like peptide 1 or insulin sensitivity in people with type 2 diabetes. Am J Clin Nutr 72: 1111-1118, 2000.

Chakravarty P, Suthar T, Coppock HA, Nicholl CG, Bloom SR, Legon S and Smith DM. British Journal of Pharmacology 130: 189-195, 2000.

Chaudhary M, Mandir N, Fitzgerald AJ, Howard JK, Lord GM, Ghatei MA, Bloom SR and Goodlad RA. Digestion 61: 223-229, 2000.

Edwards CMB, Abbott CR, Sunter D, Kim MS, Dakin CL, Murphy GK, Abusnana S, Taheri S, Rossi M and Bloom SR. Brain Res 866: 128-134, 2000.

Finer N, Bloom SR, Frost G, Banks LM and Griffiths J. Sibutramine is effective for weight loss and diabetic control in obesity with type 2 diabetes: a randomised, double-blind, placebo-controlled study. Diabetes, Obesity and Metabolism 2: 105-112, 2000.

Goldstone AP, Morgan I, Mercer JG, Morgan DGA, Moar KM, Ghatei MA and Bloom SR. Effect of leptin on hypothalamic GLP-1 peptide and brain-stem pre-proglucagon mRNA. Biochem Biophys Res Commun 269: 331-335, 2000.

Goodlad RA, Mandir N, Meeran K, Ghatei M.A., Bloom SR and Playford RJ. Does the response of the intestinal epithelium to keratinocyte growth factor vary according to the method of administration. Regul Pept 87: 83-90, 2000.

Kim MS, Rossi M, Abusnana S, Sunter D, Morgan DGA, Small CJ, Edwards CMB, Heath MM, Stanley SA, Seal LJ, Bhatti JR, Smith DM, Ghatei M.A. and Bloom SR. Hypothalamic localization of the feeding effect of agouti-related peptide and ?-melanocyte-stimulating hormone. Diabetes 49: 177-182, 2000.

Kim MS, Small CJ, Stanley SA, Morgan DGA, Seal LJ, Kong WM, Edwards CM, Abusnana S, Sunter D, Ghatei M.A. and Bloom SR. The central melanocortin system affects the hypothalamo-pituitary thyroid axis and may mediate the effect of leptin. J Clin Invest 105: 1005-1011, 2000.

Kitchen PA, Fitzgerald AJ, Goodlad RA, Barley NF, Ghatei MA, Legon S, Bloom SR, Price A, Walters JR and Forbes A. Glucagon-like peptide-2 increases sucrase-isomaltase but not caudal- related homeobox protein-2 gene expression. Am J Physiol Gastrointest Liver Physiol 278: G425-G428, 2000.

Kulkarni RN, Wang Z, Wang R-M, Smith DM, Ghatei MA and Bloom SR. J Endocrinol 165: 509-518, 2000.

Matarese G, Alviggi C, Sanna V, Howard JK, Lord GM, Carravetta C, Fontana S, Lechler RI, Bloom SR and De Placido G. Increased leptin levels in serum and peritoneal fluid of patients with pelvic endometriosis. J Clin Endocrinol Metab 85: 2483-2487, 2000.

Murphy KG, Abbott CR, Mahmoudi M, Hunter R, Gardiner JV, Rossi M, Stanley SA, Ghatei MA, Kuhar MJ and Bloom SR. J Endocrinol 166: 659-668, 2000.

Russell SH, Kim MS, Small CJ, Abbott CR, Morgan DG, Taheri S, Murphy KG, Todd JF, Ghatei MA and Bloom SR. Central administration of orexin A suppresses basal and domperidone stimulated plasma prolactin. J Neuroendocrinol 12: 1213-1218, 2000.

Salmon AL, Johnsen AH, Bienert M, McMurray G, Nandha KA, Bloom SR and Shaw C. J Biol Chem 275: 4549-4554, 2000.

Satoh F, Beak SA, Small CJ, Falzon M, Ghatei MA, Bloom SR and Smith DM. Endocrinol 141: 1301-1309, 2000.

Satoh F, Smith DM, Gardiner JV, Mahmoodi M, Murphy JK, Ghatei MA and Bloom SR. British Journal of Pharmacology 129: 1787-1793, 2000.

Seal LJ, Small CJ, Kim MS, Stanley SA, Taheri S, Ghatei MA and Bloom SR. Endocrinol 141: 1909-1912, 2000.

Stanley SA and Bloom SR. Endocrine aspects of liver tumors. In: Surgery of the Liver & Biliary Tract, edited by Blumgart L and Fong Y. Harcourt Publishers Limited, 2000, p. 1503-1520.

Stanley SA, Todd JF, Small CJ, Kim MS, Heath MM, Anand P, Ghatei M.A. and Bloom SR. J Neuroendocrinology 12: 1009-1013, 2000.

Taheri, S., Ward, H., Ghatei, M., and Bloom, S. R. Role of orexins in sleep and arousal mechanisms. Lancet 355, 847. 2000.

Taheri S, Ghatei MA and Bloom SR. Gastrointestinal hormones and tumor syndromes. In: Endocrinology, edited by Leslie J.DeGroot and J.Larry Jameson. Philadelphia: W.B. Saunders Company, 2000, p. 2547-2558.

Taheri S, Sunter D, Dakin C, Moyes S, Seal LJ, Gardiner J, Rossi M, Ghatei M and Bloom SR. Neurosci Lett 279: 109-112, 2000.

Todd JF, Edwards CMB, Ghatei MA and Bloom SR. The differential effects of galanin-(1-30) and -(3-30) on anterior pituitary hormone secretion in vivo in humans. Am J Physiol Endocrinol Metab 278: E1060-E1066, 2000.

Wren AM, Small CJ, Ward HL, Dakin C, Taheri S, Kennedy AR, Roberts GH, Morgan DGA, Ghatei MA and Bloom SR. The novel hypothalamic peptide ghrelin stimulates food intake and growth hormone secretion. Endocrinol 41: 4325-4328, 2000.

Abbott CR, Rossi M, Wren AM, Murphy KG, Kennedy AR, Stanley SA, Zollner AN, Morgan DG, Morgan I, Ghatei MA, Small CJ and Bloom SR. Evidence of an orexigenic role for cocaine- and amphetamine-regulated transcript after administration into discrete hypothalamic nuclei. Endocrinol 142: 3457-3463, 2001.

Dakin C, Gunn I, Small CJ, Edwards CMB, Hay DL, Smith DM, Ghatei MA and Bloom SR. Endocrinol 142: 4244-4250, 2001.

Dhillo, W. S. and Bloom, S. R. Hypothalamic peptides as drug targets for obesity. Current Opinion in Pharmacology 1(6), 651-655. 1-12-2001.

Edwards CMB, Stanley SA, Davis R, Brynes A, Frost G, Seal LJ, Ghatei MA and Bloom SR. Exendin-4 reduces fasting and postprandial glucose and decreases energy intake in healthy volunteers. Amer J Physiol 281: E155-E161, 2001.

Ghatei MA, Goodlad RA, Taheri S, Mandir N, Brynes AE, Jordinson M and Bloom SR. Dig Dis Sci 46: 1255-1263, 2001.

Goldstone AP, Thomas EL, Brynes AE, Bell JD, Frost G, Saeed N, Hajnal JV, Howard JK, Holland A and Bloom SR. Visceral adipose tissue and metabolic complications of obesity are reduced in Prader-Willi syndrome female adults: evidence for novel influences on body fat distribution. J Clin Endocrinol Metab 86: 4330-4338, 2001.

Kennedy A, Todd JF, Stanley SA, Abbott CR, Small CJ, Ghatei MA and Bloom SR. Melanin-concentrating hormone (MCH) suppresses thyroid stimulating hormone (TSH) release, in vivo and in vitro, via the hypothalamus and the pituitary. Endocrinol 142: 3265-3268, 2001.

Matarese G, Di Giacomo A, Sanna V, Lord GM, Howard JK, Di Tuoro A, Bloom SR, Lechler RI, Zappacosta S and Fontana S. Requirement for leptin in the induction and progression of autoimmune encephalomyelitis. J Immunol 166: 5909-5916, 2001.

Matarese G, Sanna V, Di Giacomo A, Lord GM, Howard JK, Bloom SR, Lechler RI, Fontana S and Zappacosta S. Leptin potentiates experimental autoimmune encephalomyelitis in SJL female mice and confers susceptibility to males. Eur J Immunol 31: 1324-1332, 2001.

Russell SH, Small CJ, Kennedy AR, Stanley SA, Seth A, Murphy KG, Taheri S, Ghatei M.A. and Bloom SR. Orexin A interactions in the hypothalamo-pituitary gonadal axis. Endocrinol 142: 5294-5302, 2001.

Russell SH, Small CJ, Dakin C, Abbott CR, Morgan DG, Ghatei MA and Bloom SR. J Neuroendocrinology 13: 561-566, 2001.

Russell SH, Small CJ, Stanley SA, Franks S, Ghatei M.A. and Bloom SR. The invitro role of tumour necrosis factor-alpha and interleukin-6 in the hypothalamic pituitary gonadal axis. J Neuroendocrinology 13: 296-301, 2001.

Seal LJ, Small CJ, Dhillo WS, Stanley SA, Abbott CR, Ghatei MA and Bloom SR. Endocrinol 142: 4236-4243, 2001.

Small CJ, Kim MS, Stanley SA, Mitchell JRD, Murphy K, Morgan DG, Ghatei MA and Bloom SR. Diabetes 50: 248-254, 2001.

Stanley SA, Small CJ, Murphy KG, Rayes E, Abbott CR, Seal LJ, Morgan DG, Sunter D, Dakin C, Kim MS, Hunter R, Ghatei M.A. and Bloom SR. Brain Res 893: 186-194, 2001.

Sunter D, Morgan I, Edwards CMB, Dakin C, Murphy KG, Gardiner J, Taheri S, Rayes E and Bloom SR. Brain Res 907: 27-34, 2001.

Taheri, S. and Bloom, S. R. Orexins/hypocretins: waking up the scientific world. Clinical Endocrinology 54(4), 421-429. 2001.

Taheri S, Ghatei M.A. and Bloom SR. The orexins/hypocretins - novel hypothalamic neuropeptides with multiple functions. In: Recent Research Developments in Endocrinology, edited by Pandalai S. Transworld Research Network, 2001, p. 121-133.

Taheri S, Gardiner J, Hafizi S, Murphy K, Dakin C, Seal LJ, Small CJ, Ghatei MA and Bloom SR. NeuroReport 12: 459-464, 2001.

Upton PD, Wharton J, Coppock H, Davie N, Yang X, Yacoub MH, Ghatei MA, Polak JM, Bloom SR, Smith DM and Morrell NW. Adrenomedullin expression and growth inhibitory effects in distinct pulmonary artery smooth muscle cell subpopulations. Am J Respir Cell Mol Biol 24: 170-178, 2001.

Ward HL, Small CJ, Murphy KG, Kennedy AR, Ghatei MA and Bloom SR. The actions of tuberoinfundibular peptide on the hypothalamo-pituitary axes. Endocrinol 142: 3451-3456, 2001.

Wren AM, Seal LJ, Cohen MA, Brynes AE, Frost GS, Murphy KG, Dhillo WS, Ghatei MA and Bloom SR. Ghrelin enhances appetite and increases food intake in humans. J Clin Endocrinol Metab 86: 5992-5995, 2001.

Wren AM, Small CJ, Abbott CR, Dhillo WS, Seal LJ, Cohen MA, Batterham RL, Taheri S, Stanley SA, Ghatei MA and Bloom SR. Diabetes 50: 2540-2547, 2001.

Bacon A, Holmes FE, Small CJ, Ghatei M, Mahoney S, Bloom S and Wynick D. Transgenic over-expression of galanin in injured primary sensory neurons. NeuroReport 13: 2129-2132, 2002.

Bates SH, Gardiner JV, Jones RB, Bloom SR and Bailey CJ. Acute stimulation of glucose uptake by leptin in L6 muscle cells. Horm Metab Res 34: 111-115, 2002.

Batterham RL, Cowley MA, Small CJ, Herzog H, Cohen MA, Dakin CL, Wren AM, Brynes AE, Low MJ, Ghatei MA, Cone RD and Bloom SR. Gut hormone PYY(3-36) physiologically inhibits food intake. Nature 418: 650-654, 2002.

Bloom SR, Ghatei MA and Taheri S. Glucagon- and Proglucagon-derived peptides. In: Wiley Encyclopedia of Molecular Medicine, John Wiley & Sons Inc., 2002, p. 1430-1434.

Bloom, S. R. Who's to say that the risk is worth taking? Faced with the fear that their science might be misused, what should a researcher do? New Sci. 175(2361), 25. 21-9-2002.

Brynes AE, Edwards CM, Ghatei MA, Bloom SR and Frost GS. Men at increased risk of coronary heart disease are not different from age- and weight-matched healthy controls in their postprandial triglyceride, nonesterified fatty acid, or incretin responses to sucrose. Metabolism 51: 195-200, 2002.

Calam J, Taheri S and Bloom SR. Gastrinoma. In: Oxford Textbook of Endocrinology and Diabetes, edited by Wass JAH and Shalet SM. Oxford University Press, 2002, p. 877-882.

Choksi T, Hay DL, Legon S, Poyner DR, Hagner S, Bloom SR and Smith DM. Comparison of the expression of calcitonin receptor-like receptor (CRLR) and receptor activity modifying proteins (RAMPs) with CGRP and adrenomedullin binding in cell lines. Br J Pharmacol 136: 784-792, 2002.

Dakin CL, Small CJ, Park AJ, Seth A, Ghatei MA and Bloom SR. Am J Physiol Endocrinol Metab 283: E1173-E1177, 2002.

Dhillo WS, Small CJ, Seal LJ, Kim MS, Stanley SA, Murphy KG, Ghatei MA and Bloom SR. Neuroendocrinol 75: 209-216, 2002.

Dhillo WS, Small CJ, Stanley SA, Jethwa PH, Seal LJ, Murphy KG, Ghatei MA and Bloom SR. J Neuroendocrinol 14: 725-730, 2002.

English PJ, Ghatei MA, Malik IA, Bloom SR and Wilding JP. Food fails to suppress ghrelin levels in obese humans. J Clin Endocrinol Metab 87: 2984-2987, 2002.

Fitzgerald AJ, Ghatei MA, Mandir N, Bloom SR, Iversen L and Goodlad RA. Digestion 66: 58-66, 2002.

Frankton S and Bloom SR. Glucagonoma. In: Oxford Textbook of Endocrinology and Diabetes, edited by Wass JAH and Shalet SM. Oxford University Press, 2002, p. 889-894.

Goldstone AP, Unmehopa UA, Bloom SR and Swaab DF. Hypothalamic NPY and agouti-related protein are increased in human illness but not in Prader-Willi syndrome and other obese subjects. J Clin Endocrinol Metab 87: 927-937, 2002.

Goldstone AP, Brynes AE, Thomas EL, Bell JD, Frost G, Holland A, Ghatei MA and Bloom SR. Resting metabolic rate, plasma leptin concentrations, leptin receptor expression, and adipose tissue measured by whole-body magnetic resonance imaging in women with Prader-Willi syndrome. Am J Clin Nutr 75: 468-475, 2002.

Goldstone AP, Howard JK, Lord GM, Ghatei MA, Gardiner JV, Wang ZL, Wang RM, Girgis SI, Bailey CJ and Bloom SR. Biochem Biophys Res Commun 295: 475-481, 2002.

Howard JK, Ghatei MA and Bloom SR. Bombesin. In: Wiley Encyclopedia of Molecular Medicine, John Wiley & Sons Ltd, 2002, p. 381-383.

Howard JK and Bloom SR. VIPomas. In: Oxford Textbook of Endocrinology and Diabetes, Oxford University Press, 2002, p. 895-899.

Kim MS, Small CJ, Russell SH, Morgan DGA, Abbott CR, AlAhmed SH, Hay DL, Ghatei MA, Smith DM and Bloom SR. Effects of melanocortin receptor ligands on thyrotropin-releasing hormone release: evidence for the differential roles of melanocortin 3 and 4 receptors. J Neuroendocrinol 14: 276-282, 2002.

Kim MS, Rossi M, Abbott CR, AlAhmed SH, Smith DM and Bloom SR. Sustained orexigenic effect of Agouti related protein may be not mediated by the melanocortin 4 receptor. Peptides 23: 1069-1076, 2002.

Lord GM, Matarese G, Howard JK, Bloom SR and Lechler RI. Leptin inhibits the anti-CD3-driven proliferation of peripheral blood T cells but enhances the production of proinflammatory cytokines. J Leukoc Biol 72: 330-338, 2002.

Owji AA, Khoshdel Z, Sanea F, Panjehshahin MR, Shojaee FM, Smith DM, Coppock HA, Ghatei MA and Bloom SR. Brain Res 929: 70-75, 2002.

Russell SH, Small CJ, Sunter D, Morgan I, Dakin CL, Cohen MA and Bloom SR. Regul Pept 104: 61-68, 2002.

Seal LJ, Small CJ, Dhillo WS, Kennedy AR, Ghatei MA and Bloom SR. Prolactin-Releasing Peptide Releases Corticotropin-Releasing Hormone and Increases Plasma Adrenocorticotropin via the Paraventricular Nucleus of the Hypothalamus. Neuroendocrinol 76: 70-78, 2002.

Seal LJ, Ghatei MA and Bloom SR. Secretin. In: Wiley Encyclopedia of Molecular Medicine, John Wiley & Sons Inc., 2002, p. 2871-2874.

Small, C. J., Stanley, S. A., and Bloom, S. R. Appetite control and reproduction: leptin and beyond. Semin.Reprod.Med. 20(4), 389-398. 2002.

Stanley SA, Ghatei MA and Bloom SR. Pancreatic polypeptide. In: Wiley Encyclopedia of Molecular Medicine, John Wiley & Sons Inc., 2002, p. 2381-2384.

Taheri S, Ghatei MA and Bloom SR. Endocrinology of the Gastrointestinal Tract. In: Comprehensive Clinical Endocrinology, edited by Besser GM and Thorner MO. Moseby, 2002, p. 453-469.

Taheri S, Ghatei MA and Bloom SR. Cholecystokinin (CCK). In: Wiley Encyclopedia of Molecular Medicine, John Wiley & Sons Inc., 2002, p. 752-754.

Taheri S, Ghatei MA and Bloom SR. Vasoactive intestinal peptide (VIP). In: Wiley Encyclopedia of Molecular Medicine, John Wiley & Sons Inc., 2002, p. 3344-3346.

Taheri S, Murphy K, Cohen M, Sujkovic E, Kennedy A, Dhillo W, Dakin C, Sajedi A, Ghatei M and Bloom S. Biochem Biophys Res Commun 291: 1208-1212, 2002.

Taheri S, Ghatei MA and Bloom SR. Orexins (Hypocretins). In: Wiley Encyclopedia of Molecular Medicine, John Wiley & Sons Inc., 2002, p. 2328-2331.

Todd JF and Bloom SR. Insulinomas and hypoglycaemia. In: Oxford Textbook of Endocrinology and Diabetes, edited by Wass JAH and Shalet SM. Oxford University Press, 2002, p. 883-888.

Wren, A. M. and Bloom, S. R. How appetite is controlled. Current Opinion in Endocrinology & Diabetes 9, 145-151. 2002.

Wren AM, Small CJ, Abbott CR, Jethwa PH, Kennedy AR, Murphy KG, Stanley SA, Zollner AN, Ghatei MA and Bloom SR. Hypothalamic actions of neuromedin U. Endocrinol 143: 4227-4234, 2002.

Wren AM, Small CJ, Fribbens CV, Neary NM, Ward HL, Seal LJ, Ghatei MA and Bloom SR. The hypothalamic mechanisms of the hypophysiotropic action of ghrelin. Neuroendocrinol 76: 316-324, 2002.

Abbott CR, Kennedy AR, Wren AM, Rossi M, Murphy KG, Seal LJ, Todd JF, Ghatei MA, Small CJ and Bloom SR. Identification of hypothalamic nuclei involved in the orexigenic effect of melanin-concentrating hormone. Endocrinol 144: 3943-3949, 2003.

Barakat MT, Lynn JA and Bloom SR. Endocrine Tumors of the Gastrointestinal Tract. In: Endocrine Surgery, edited by Schwartz AE, Pertsemlidis D and Gagner M. New York: Marcel Dekker, 2003, p. 643-658.

Batterham RL, le Roux CW, Cohen MA, Park AJ, Ellis SM, Patterson M, Frost GS, Ghatei MA and Bloom SR. Pancreatic polypeptide reduces appetite and food intake in humans. J Clin Endocrinol Metab 88: 3989-3992, 2003.

Batterham, R. L. and Bloom, S. R. The gut hormone peptide YY regulates appetite. Annals of the New York Academy of Sciences 994, 162-168. 2003.

Batterham RL, Cohen MA, Ellis SM, le Roux CW, Withers DJ, Frost GS, Ghatei MA and Bloom SR. Inhibition of food intake in obese subjects by peptide YY3-36. N Engl J Med 349: 941-948, 2003.

Bloom, S. R. The fat controller. New Sci. 179(2407), 38. 2003.

Brynes AE, Mark EC, Ghatei MA, Dornhorst A, Morgan LM, Bloom SR and Frost GS. A randomised four-intervention crossover study investigating the effect of carbohydrates on daytime profiles of insulin, glucose, non-esterified fatty acids and triacylglycerols in middle-aged men. Br J Nutr 89: 207-218, 2003.

Chowdhury, T. A., Bloom, S., and Cramb, R. A career in metabolic medicine. British Medical Journal 326(7403), s205-s206. 21-6-2003.

Cohen MA, Ellis SM, le Roux CW, Batterham RL, Park A, Patterson M, Frost GS, Ghatei MA and Bloom SR. Oxyntomodulin suppresses appetite and reduces food intake in humans. J Clin Endocrinol Metab 88: 4696-4701, 2003.

Dhillo WS, Small CJ, Jethwa PH, Russell SH, Gardiner JV, Bewick GA, Seth A, Murphy KG, Ghatei MA and Bloom SR. Paraventricular nucleus administration of calcitonin gene-related peptide inhibits food intake and stimulates the hypothalamo-pituitary-adrenal axis. Endocrinol 144: 1420-1425, 2003.

Dhillo WS, Small CJ, Gardiner JV, Bewick GA, Whitworth EJ, Jethwa PH, Seal LJ, Ghatei MA, Hinson JP and Bloom SR. Biochem Biophys Res Commun 301: 102-107, 2003.

Druce, M. and Bloom, S. R. Central regulators of food intake. Curr.Opin.Clin.Nutr.Metab Care 6(4), 361-367. 2003.

Frost GS, Brynes AE, Dhillo WS, Bloom SR and McBurney MI. The effects of fiber enrichment of pasta and fat content on gastric emptying, GLP-1, glucose, and insulin responses to a meal. Eur J Clin Nutr 57: 293-298, 2003.

Kennedy AR, Todd JF, Dhillo WS, Seal LJ, Ghatei MA, O'Toole CP, Jones M, Witty D, Winborne K, Riley G, Hervieu G, Wilson S and Bloom SR. Effect of Direct Injection of Melanin-Concentrating Hormone into the Paraventricular Nucleus: Further Evidence for a Stimulatory Role in the Adrenal Axis via SLC-1. J Neuroendocrinol 15: 268-272, 2003.

Kong WM, Stanley S, Gardiner J, Abbott C, Murphy K, Seth A, Connoley I, Ghatei M, Stephens D and Bloom S. A role for arcuate cocaine and amphetamine-regulated transcript in hyperphagia, thermogenesis, and cold adaptation. FASEB J 17: 1688-1690, 2003.

le Roux, C. W. and Bloom, S. R. Clinical authorization: what is best for the patient? Ann.Clin.Biochem. 40(Pt 2), 113-114. 2003.

Murray CDR, Kamm MA, Bloom SR and Emmanuel AV. Ghrelin for the Gastroenterologist: History and Potential. Gastroenterology 125: 1492-1502, 2003.

Neary, N. M., Small, C. J., and Bloom, S. R. Gut and Mind. Gut 52(7), 918-921. 2003.

Seth A, Stanley S, Jethwa P, Gardiner J, Ghatei M and Bloom S. Galanin-like peptide stimulates the release of gonadotropin-releasing hormone in vitro and may mediate the effects of leptin on the hypothalamo-pituitary-gonadal axis. Endocrinol 2003.

Seth A, Stanley S, Dhillo W, Murphy K, Ghatei M and Bloom S. Effects of galanin-like Peptide on food intake and the hypothalamo-pituitary-thyroid axis. Neuroendocrinol 77: 125-131, 2003.

Small CJ, Goubillon ML, Murray JF, Siddiqui A, Grimshaw SE, Young H, Sivanesan V, Kalamatianos T, Kennedy AR, Coen CW, Bloom SR and Wilson CA. Endocrinol 144: 3225-3236, 2003.

Small CJ, Liu YL, Stanley SA, Connoley IP, Kennedy A, Stock MJ and Bloom SR. Chronic CNS administration of Agouti-related protein (Agrp) reduces energy expenditure. Int J Obes Relat Metab Disord 27: 530-533, 2003.

Stanley SA, Davies S, Small CJ, Gardiner JV, Ghatei MA, Smith DM and Bloom SR. gamma-MSH increases intracellular cAMP accumulation and GnRH release in vitro and LH release in vivo. FEBS Lett 543: 66-70, 2003.

Ward H, Gardiner J, Kong WM, Murphy K and Bloom S. Distribution of fluorescence following injection of recombinant adeno-associated virus encoding green fluorescent protein into the paraventricular nucleus. Neuroendocrinol 77: 100-104, 2003.

Andersson U, Filipsson K, Abbott CR, Woods A, Smith K, Bloom SR, Carling D and Small CJ. AMP-activated protein kinase plays a role in the control of food intake. J Biol Chem 279: 12005-12008, 2004.

Barakat, M. T., Meeran, K., and Bloom, S. R. Neuroendocrine tumours. Endocr.Relat Cancer 11(1), 1-18. 2004.

Dakin CL, Small CJ, Batterham RL, Neary NM, Cohen MA, Patterson M, Ghatei MA and Bloom SR. Endocrinol 145: 2687-2695, 2004.

Dhillo WS and Bloom SR. Gastrointestinal Hormones and Regulation of Food Intake. Horm Metab Res 36: 1-6, 2004.

Druce MR, Small CJ and Bloom SR. Minireview: Gut peptides regulating satiety. Endocrinol 145: 2660-2665, 2004.

Goldstone AP, Thomas EL, Brynes AE, Castroman G, Edwards R, Ghatei MA, Frost G, Holland AJ, Grossman AB, Korbonits M, Bloom SR and Bell JD. Elevated fasting plasma ghrelin in prader-willi syndrome adults is not solely explained by their reduced visceral adiposity and insulin resistance. J Clin Endocrinol Metab 89: 1718-1726, 2004.

Kong WM, Martin NM, Smith K, Gardiner JV, Connoley IP, Stephens D, Dhillo WS, Ghatei MA, Small CJ and Bloom SR. Triiodothyronine stimulates food intake via the hypothalamic ventromedial nucleus independent of changes in energy expenditure. Endocrinol 145: 5252-5258, 2004.

Mahmoodi M, Gardiner JV, Ghatei MA, Asadikaram G and Bloom SR. Clin Biochem 37: 217-223, 2004.

Malik IA, English PJ, Ghatei MA, Bloom SR, MacFarlane IA and Wilding JP. The relationship of ghrelin to biochemical and anthropometric markers of adult growth hormone deficiency. Clin Endocrinol (Oxf) 60: 137-141, 2004.

Martin NM, Small CJ, Sajedi A, Patterson M, Ghatei MA and Bloom SR. Int J Obes Relat Metab Disord 28: 886-893, 2004.

Martin NM, Small CJ, Sajedi A, Xiao HL, Weiss RE, Gardiner JV, Ghatei MA and Bloom SR. Regul Pept 122: 169-172, 2004.

McGowan B and Bloom S. Peptide YY and appetite control. Current Opinion in Pharmacology 2004: 583-588, 2004.

Murphy KG and Bloom SR. Gut hormones in the control of appetite. Exp Physiol 89.5: 507-516, 2004.

Neary NM, Small CJ, Wren AM, Lee JL, Druce MR, Palmieri C, Frost GS, Ghatei MA, Coombes RC and Bloom SR. Ghrelin increases energy intake in cancer patients with impaired appetite: acute, randomized, placebo-controlled trial. J Clin Endocrinol Metab 89: 2832-2836, 2004.

Neary NM, Goldstone AP and Bloom SR. Appetite regulation: from the gut to the hypothalamus. Clin Endocrinol (Oxf) 60: 153-160, 2004.

Park, A. and Bloom, S. R. Peptides and obesity: the PYY(3-36) story. Regulatory Peptides 119(1-2), 1-2. 15-6-2004.

Park, A., le Roux, C. W., and Bloom, S. R. Clinical biochemistry. BMJ Careers 328(7445), 153-154. 2004.

Small, C. J., Stanley, S. A., and Bloom, S. R. Neuropeptide regulation of appetite and reproduction. Journal Fur Reproduktionsmedizin Und Endokrinologie (1/2004), 13-19. 2004.

Small, C. J., Carling, D., and Bloom, S. R. Cellular energy sensor balances the scales. Nat.Med. 10(7), 681-682. 2004.

Small CJ and Bloom SR. Gut Hormones as Peripheral Anti Obesity Targets. Current Drug Targets 3: 379-388, 2004.

Small CJ and Bloom SR. Gut hormones and the control of appetite. Trends in Endocrinology and Metabolism 15: 259-263, 2004.

Stanley S, Wynne K and Bloom S. Gastrointestinal Satiety Signals III. Glucagon-like peptide 1, oxyntomodulin, peptide YY, and pancreatic polypeptide. Am J Physiol Gastrointest Liver Physiol 286: G693-G697, 2004.

Stanley SA, Murphy KG, Bewick GA, Kong WM, Opacka-juffry J, Gardiner JV, Ghatei M, Small CJ and Bloom SR. Am J Physiol Endocrinol Metab 287: E583-E590, 2004.

Thompson E.L., Murphy KG, Todd JF, Martin NM, Small CJ, Ghatei MA and Bloom SR. Chronic administration of NMU into the paraventricular nucleus stimulates the HPA axis but does not influence food intake or body weight. Biochem Biophys Res Commun 323: 65-71, 2004.

Thompson E.L., Patterson M, Murphy KG, Smith K, Dhillo W, Todd JF, Ghatei M.A. and Bloom SR. Central and peripheral administration of kisspeptin-10 stimulates the hypothalamic-pituitary-gonadal axis. Journal of Neuroendocrinology 16: 850-858, 2004.

Wynne K, Stanley S and Bloom S. The gut and regulation of body weight. J Clin Endocrinol Metab 89: 2576-2582, 2004

Abbott CR, Monteiro M, Small CJ, Sajedi A, Smith KL, Parkinson JRC, Ghatei M and Bloom SR. The inhibitory effects of peripheral administration of peptide YY3-36 and glucagon-like peptide-1 on food intake are attenuated by ablation of the vagal-brainstem-hypothalamic pathway. Brain Res 1044: 127-131, 2005.

Abbott CR, Small CJ, Sajedi A, Smith KL, Parkinson JR, Broadhead LL, Ghatei MA and Bloom SR. Int J Obes EPub Oct 2005: 2005.

Abbott CR, Small CJ, Kennedy AR, Neary NM, Sajedi A, Ghatei M and Bloom SR. Blockade of the neuropeptide Y Y2 receptor with the specific antagonist BIIE0246 attenuates the effect of endogenous and exogenous peptide YY(3-36) on food intake. Brain Res 1043: 139-144, 2005.

Andersson U, Treebak J, Nielsen J, Smith K, Abbott C, Small CJ, Carling D and Richter E. Biochem Biophys Res Commun 329: 719-725, 2005.

Barakat, M. T. and Meeran, K. Neuroendocrine tumors and gut hormones. Current Opinion in Endocrinology & Diabetes 12(1), 99-105. 2005.

Bewick GA, Dhillo W, Darch SJ, Murphy KG, Gardiner JV, Jethwa PH, Kong WM, Ghatei M.A. and Bloom SR. Hypothalamic cocaine and amphetamine regulated transcript (CART) and agouti related protein (AGRP) neurons co-express the NOP1 receptor and nociceptin alters CART and AgRP release. Endocrinol 146: 2005.

Bewick GA, Gardiner J, Dhillo W, Kent A, White N, Webster Z, Ghatei M.A. and Bloom SR. FASEB E-Pub August 2005: 2005.

Bloom S, Wynne K and Chaudhri O. Gut feeling - the secret of satiety? Clinical Medicine 5: 147-152, 2005.

Dhillo W, Jayasena CNL, Jackson JE, Lynn JA, Bloom S, Meeran K and Todd JF. Localization of gastrinomas by selective intra-arterial calcium injection in patients on proton pump inhibitor or H2 receptor antagonist therapy. European Journal of Gastroenterology & Hepatology 17: 429-433, 2005.

Dhillo W, Chaudhri O, Patterson M, Thompson EL, Murphy GK, Murphy GK, Badman MK, McGowan BM, Amber V, Patel S, Ghatei MA and Bloom SR. Kisspeptin-54 stimulates the hypothalamic-pituitary gonadal axis in human males. J Clin Endo & Metab 90: 6609-6615, 2005.

Dhillo WS, Gardiner JV, Castle L, Bewick GA, Smith KL, Meeran K, Todd JF, Ghatei MA and Bloom SR. Agouti related protein (AgRP) is upregulated in Cushing's Syndrome. Exp Clin Endocrinol Diabetes 113: 602-606, 2005.

Druce M, Wren AM, Park AJ, Milton JE, Patterson M, Frost G, Ghatei M.A., Small C and Bloom SR. Ghrelin increases food intake in obese as well as lean subjects. Int J Obes Relat Metab Disord EPub May: 2005.

Druce MR, Neary NM, Small CJ, Milton J, Monteiro M, Patterson M, Ghatei MA and Bloom SR. Subcutaneous administration of ghrelin stimulates energy intake in helathy lean human volunteers. Int J Obes E-Pub Oct 2005: 2005.

Feinle-Bisset C, Patterson M, Ghatei M.A., Bloom SR and Horowitz M. Fat digestion is required for the suppression of ghrelin and stimulation of peptide YY and pancreatic polypeptide secretion by intraduodenal lipid. Am J Physiol Endocrinol Metab Epub July, 2005.

Forbes S, Moonan M, Robinson S, Anyaoku V, Patterson M, Murphy KG, Ghatei M, Bloom SR and Johnston DG. Impaired circulating glucagon-like peptide-1 response to oral glucose in women with previous gestational diabetes. Clin Endocrinol 62: 51-55, 2005.

Gardiner J, Kong WM, Ward H, Murphy KG, Dhillo W and Bloom SR. AAV mediated expression of anti-sense neuropeptide Y cRNA in the arcuate nucleus of rats results in decreased weight gain and food intake. Biochem Biophys Res Commun 327: 1088-1093, 2005.

Goldstone AP, Patterson M, Kalingag N, Ghatei M.A., Brynes AE, Bloom S, Grossman AB and Korbonits M. Fasting and postprandial hyperghrelinemia in Prader-Willi syndrome is partially explained by hypoinsulinemia, and is not due to peptide YY3-36 deficiency or seen in hypothalamic obesity due to craniopharyngioma. J Clin Endocrinol Metab 90: 2681-2690, 2005.

Jethwa PH, Small CJ, Smith KL, Seth A, Darch SJ, Abbott CR, Murphy KG, Todd JF, Ghatei M.A. and Bloom SR. Neuromedin U has a physiological role in the regulation of food intake and may partially mediate the effect of leptin. Am J Physiol Endocrinol Metab 289: E301-E305, 2005.

Kitchen PA, Goodlad RA, Fitzgerald AJ, Mandir N, Ghatei M.A., Bloom SR, Berlanga-Acosta J, Playford RJ, Forbes A and Walters JR. Intestinal Growth in Parenterally-Fed Rats Induced by the Combined Effects of Glucagon-like Peptide 2 and Epidermal Growth Factor. J Parenter Enteral Nutr 29: 248-254, 2005.

le Roux CW, Batterham RL, Aylwin SJ, Patterson M, Borg CM, Wynne KJ, Kent A, Vincent RP, Gardiner J, Ghatei MA and Bloom SR. Attenuated peptide YY release in obese subjects is associated with reduced satiety. Endocrinol EPub Sept, 2005.

le Roux CW. Peptide YY, appetite and food intake. Proc Nutr Soc 64: 213-216, 2005.

le Roux CW, Neary NM, Halsey TJ, Small CJ, Martinez-Isla AM, Ghatei M.A., Theodorou NA and Bloom SR. Ghrelin does not stimulate food intake in patients with surgical procedures involving vagotomy. J Clin Endocrinol Metab 90: 4521-4524, 2005.

le Roux CW, Patterson M, Vincent RP, Hunt C, Ghatei M.A. and Bloom SR. Postprandial plasma ghrelin is suppressed proportion to meal calorie content in normal-weight but not obese subjects. J Clin Endo & Metab 90: 1068-1071, 2005.

le Roux CW and Bloom SR. Editorial: Why do patients lose weight after Roux-en-Y gastric bypass J Clin Endocrinol Metab 90: 591-592, 2005.

le Roux CW, Ghatei M.A., Gibbs JS and Bloom SR. The putative satiety hormone PYY is raised in cardiac cachexia associated with primary pulmonary hypertension. Heart 91: 241-242, 2005.

Mahmoodi M, Gardiner J, Asadi Karam GR, Khaksari M, Murphy KG, Ghatei MA and Bloom SR. Regul Pept 132: 80-84, 2005.

Martin NM, Houston PA, Patterson M, Sajedi A, Carmignac DF, Ghatei M.A., Bloom SR and Small C. Int J Obes E- Pub September 2005: 2005.

Murphy KG and Bloom SR. Peripheral influences on central melanocortin neurones. Peptides EPub June: 2005.

Murphy, K. G., Abbott, C. R., and Bloom, Stephen R. Gut Hormones come of age. Current Opinion in Endocrinology & Diabetes 12(1), 53-55. 2005.

Murray CD, Martin NM, Patterson M, Taylor S, Ghatei MA, Kamm MA, Johnston C and Bloom SR. Ghrelin enhances gastric emptying in diabetic gastroparesis: a double-blind, placebo-controlled, cross-over study. Gut EPub Aug, 2005.

Neary NM, Small C, Druce M, Park A, Ellis SM, Senapati A, Dakin C, Fillipson K, Wang F, Kent AS, Frost GS, Ghatei MA and Bloom SR. Peptide YY3-36 and glucagon-like peptide-17-36 inhibit food intake additively. Endocrinol EPub Aug, 2005.

Neary NM, Druce MR, Small CJ and Bloom SR. Acylated ghrelin stimulates food intake in the fed and fasted states but desacylated ghrelin has no effect. Gut 55: 135, 2005.

Park, A. J. and Bloom, Stephen R. Neuroendocrine control of food intake. Current Opinion Gastroenterol 21(2), 228-233. 1-3-2005.

Patel AD, Stanley SA, Murphy KG, Frost GS, Gardiner JV, Kent AS, White NE, Ghatei MA and Bloom SR. Ghrelin stimulates insulin-induced glucose uptake in adipocytes. Regul Pept E-Pub Dec 2005: 2005.

Patterson M, Murphy KG, le Roux CW, Ghatei M and Bloom SR. Characterization of ghrelin-like immunoreactivity in human plasma. The Journal of Endocrinology and Metabolism 90: 2205-2211, 2005.

Small CJ and Bloom A. The therapeutic potential of gut hormone peptide YY3-36 in the treatment of obesity. Expert Opinion in Investigational Drugs 14: 647-653, 2005.

Small CJ, Parkinson JRC and Bloom SR. Novel therapeutic targets for appetite regulation. Current Opinion in Investigational Drugs 6: 369-372, 2005.

Stock S, Leichner P, Wong ACK, Ghatei M, Kieffer TJ, Bloom SR and Chanoine J-P. Ghrelin, peptide YY, glucose-dependent insulinotropic polypeptide, and hunger responses to a mixed meal in anorexic, obese, and control female adolescents. The Journal of Endocrinology and Metabolism 90: 2161-2174, 2005.

Wynne K, Gianitsopoulou K, Small CJ, Patterson M, Frost G, Ghatei M.A., Brown EA, Bloom SR and Choi P. Subcutaneous ghrelin enhances acute food intake in malnourished patients who receive maintenance peritoneal dialysis: a randomized, placebo-controlled trial. Journal of American Society of Nephrology 16: 2111-2118, 2005.

Wynne K, Park AJ, Small CJ, Patterson M, Ellis SM, Murphy KG, Wren AM, Frost GS, Meeran K, Ghatei M.A. and Bloom SR. Subcutaneous oxyntomodulin reduces body weight in overweight and obese subjects: a double blind, randomized, controlled trial. Diabetes 54: 2390-2395, 2005.

Wynne K, Stanley S, McGowan B and Bloom SR. Appetite control. Endocrinol 184: 291-318, 2005.

Borg CM, le Roux CW, Ghatei MA, Bloom SR, Patel AG and Aylwin SJ. Progressive rise in gut hormone levels after Roux-en-Y gastric bypass suggets gut adaptation and explains altered satiety. Br-J-Surg 93: 210-215, 2006.

Druce M and Bloom SR. The regulation of appetite. Arch Dis Child 91: 183-187, 2006.

le Roux CW, Aylwin SJ, Batterham RL, Borg CM, Coyle F, Prasad V, Shurey S, Ghatei MA, Patel AG and Bloom SR. Gut hormone profiles following bariatric surgery favor an anorectic state, facilitate weight loss, and improve metabolic parameters. Ann Surg 243: 108-114, 2006.

Martin NM, Smith KL, Bloom SR and Small CJ. Interactions between the melanocortin system and the hypothalamo-pituitary-thyroid axis. Peptides 27: 333-339, 2006.

Murphy KG and Bloom SR. Are all fats created equal? Nat Med 12: 32-33, 2006.

Nematy M, O'Flynn JE, Wandrag L, Brynes AE, Brett SJ, Patterson M, Ghatei M.A., Bloom SR and Frost G. Changes in appetite related gut hormones in intensive care unit patients: a pilot cohort study. Critical Care 23: E-Pub Jan, 2006.

Back to the top